Seizure associated with topical cyclopentolate: a case report
Authors: Suad Al-Sulaimani , Hassan Al-Balushi , Fatema AL-Shukaili , Waleed AL-Sukaiti
Abstract
Introduction: Cyclopentolate is a widely used mydriatic agent with a rapid onset cycloplegic effect. Systemic toxicity from an ophthalmic application is uncommon. Case Presentation: We present a case of a 13-year-old girl who presented to the emergency department with a generalized seizure after receiving 1% cyclopentolate for three drops in each eye, over 15 minutes, as instructed by the prescriber. The seizure began 30 minutes after receiving the last dose. We also describe the general presentation, characteristics of affected patients, and management of this adverse drug event. Cyclopentolate systemic toxicity is dose-dependent. Conclusion: This case highlights the importance of caution when using topical ophthalmic cycloplegics in children.Keywords: Cyclopentolate 1%, eye drops, cycloplegic, seizure, case report, ophthalmic eye drops, case report
Pubmed Style
Suad Al-Sulaimani, Hassan Al-Balushi, Fatema AL-Shukaili, Waleed AL-Sukaiti. Seizure associated with topical cyclopentolate: a case report. SJE Med. 2023; 21 (February 2023): 076-079. doi:10.24911/SJEMed/72-1664129458
Publication History
Received: September 25, 2022
Accepted: January 06, 2023
Published: February 21, 2023
Authors
Suad Al-Sulaimani
Department of Emergency Medicine, Division of Medical Toxicology, Emory University School of Medicine, Atlanta, Georgia, Georgia Poison Center, Atlanta, Georgia, Department of Emergency Medicine, Armed Forces Hospital, Muscat, Oman
Hassan Al-Balushi
Department of Emergency Medicine, Division of Medical Toxicology, Emory University School of Medicine, Atlanta, Georgia, Georgia Poison Center, Atlanta, Georgia, Department of Emergency Medicine, Suhar Regional Hospital, MOH, Muscat, Oman
Fatema AL-Shukaili
Department of Emergency Medicine, Ibri Regional Hospital, MOH, Muscat, Oman
Waleed AL-Sukaiti
Department of Emergency Medicine, Ibri Regional Hospital, MOH, Muscat, Oman Oman Poison Control Center, MOH, Muscat, Oman.